Description

POSACONAZOLE

POSACONAZOLE is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections when other antifungal medicines have not worked, or you have had to stop taking them. It is also indicated for preventing invasive Aspergillus and Candida infections in patients at high risk of developing these infections due to being severely immunocompromised, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

POSACONAZOLE contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Take POSACONAZOLE as prescribed by your doctor. You are advised to take POSACONAZOLE for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood. Most of these side effects of POSACONAZOLE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in POSACONAZOLE or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe POSACONAZOLE only if the benefits outweigh the risk. Before taking the POSACONAZOLE, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of POSACONAZOLE

• Fungal infections
• Prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.

Medicinal Benefits

Posaconazole is an antifungal medication present in POSACONAZOLE. It is effective in treating fungal infections in adults. It is also indicated for preventing invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it. Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of POSACONAZOLE

• Diarrhoea
• Nausea
• Fever
• Vomiting
• Headache
• Coughing
• Low potassium levels in the blood