Description

Febuxostat Tablets

FEBUXOSTAT belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, widely used to prevent severe gout attacks or flares. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints. It is characterized by intense pain and swelling at the affected joints. FEBUXOSTAT prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.

FEBUXOSTAT contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body make uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. FEBUXOSTAT is used to prevent gout attacks or flares.

Your doctor will advise you on how often you take off the FEBUXOSTAT based on your medical condition. The common side effects of FEBUXOSTAT nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (oedema). Most of these side effects of FEBUXOSTAT do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking a FEBUXOSTAT of your own. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks. Inform your doctor if you have allergic to FEBUXOSTAT or any other medicines, have a heart problem (FEBUXOSTAT may cause heart problems that can lead to heart attack), or have kidney/liver disease. Some people experience more gout flare-ups when you start taking FEBUXOSTAT. You should continue taking this drug even if gout flare-ups occur. Your doctor may give you combination therapy to prevent flare-ups when you start FEBUXOSTAT. The safety and effectiveness of children under 18 years of age have not been established, so FEBUXOSTAT should not be given to them. If you are pregnant or breastfeeding, it is advised to inform your doctor before using FEBUXOSTAT.

Uses of FEBUXOSTAT

Treatment of severe gout, prevention of gout attacks.

Medicinal Benefits

FEBUXOSTAT is a class of medications called xanthine oxidase (enzyme that helps your body to make the uric acid) inhibitors. It works by inhibiting the enzyme xanthine oxidase, thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. FEBUXOSTAT is used to prevent gout attacks or flares.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight.

Side Effects of FEBUXOSTAT

• Nausea
• Rash
• Dizziness
• Diarrhoea
• Joint pain
• Rash,
• Inaccurate liver function test results
• Gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night)
• Localized swelling due to retention of fluids in tissues (oedema)

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In-Depth Precautions and Warning

Drug Warnings

You should avoid taking FEBUXOSTAT if you are allergic to FEBUXOSTAT, or have heart-related problems, as it increases the risk of a heart attack. It should be used cautiously in patients with kidney problems and blood disorders. Caution is required before taking FEBUXOSTAT if you are pregnant, planning to become pregnant, or already a breastfeeding mother. The safety and effectiveness of children under 18 years of age have not been established, so FEBUXOSTAT should not be given to them.

Drug Interactions

Drug-Drug Interactions: FEBUXOSTAT interacts with anticancer medications (mercaptopurine, methotrexate), immunosuppressant medications (azathioprine), antidiabetic medications (rosiglitazone), and antiasthma medications (theophylline).

Drug-Food Interactions: Intake of alcohol may increase the risk of side effects, so avoid taking alcohol with FEBUXOSTAT. Limit the purine-rich diet.

Drug-Disease Interactions: Brief your doctor if you have a medical history of allergic reactions to medicines,  hyperuricemia (an abnormally high level of uric acid in the blood), heart diseases, liver or kidney diseases before taking FEBUXOSTAT.

Drug-Drug Interactions Checker List:

• MERCAPTOPURINE
• METHOTREXATE
• AZATHIOPRINE
• THEOPHYLLINE
• ROSIGLITAZONE